Vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder
Neuropsychiatric Disease and Treatment 2018:14 581-585
Nilfer sahin1 nilfersahin at hotmail.com ,Hatice Altun2 Ergul Belge Kurutas3 Damla Balkan1
1 Dept of Child and Adolescent Psychiatry, Mugla Sitki Kogrnan University, Mugla, Turkey;
2 Dept of Child and Adolescent Psychiatry, Kahramanmaras Sutcu Imam U., Kahramanmaras, Turkey;
3 Dept of Biochemistry, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey
- Omega-3 and Vitamin D each treat many mental health problems - April 2018
- ADHD in children 2.6 X more likely if low vitamin D – meta-analysis Feb 2018
- ADHD 2 times more likely if poor Omega-6 to Omega-3 ratio – meta-analysis May 2016
- ADHD category listing has
52 items along with related searches
Vitamin D Receptor category has the following
530 studies in Vitamin D Receptor category Vitamin D tests cannot detect Vitamin D Receptor (VDR) problems
See also:
A poor VDR restricts Vitamin D from getting in the cells48 studies in the Resveratrol category It appears that 30% of the population have a poor VDR (40% of the Obese )
Health problems include: Autoimmune (
Several diseases protect themselves by deactivating the Vitamin D receptor. Example: Breast Cancer
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The Vitamin D Receptor is associated with many health problems19 studies), Breast Cancer ( 24 studies), Colon Cancer ( 13 studies), Cardiovascular ( 23 studies), Cognition ( 16 studies), Diabetes ( 24 studies), Hypertension ( 9 studies), Infant ( 22 studies), Lupus ( 6 studies), Metabolic Syndrome ( 4 studies), Mortality ( 4 studies), Multiple Sclerosis ( 14 studies), Obesity ( 17 studies), Pregnancy ( 24 studies), Rheumatoid Arthritis ( 10 studies), TB ( 8 studies), VIRUS ( 37 studies), Click here for details
Some health problems, such as Breast Cancer, Diabetes, and COVID protect themselves by reducing VDR activation
55 health problems associated with poor VDR
A poor VDR is associated with the risk of 55 health problems click here for details
The risk of 48 diseases at least double with poor VDR as of Jan 2023 click here for details
Some health problem, such as Breast Cancer reduce the VDRVDR at-home test $29 - results not easily understood in 2016
There are hints that you may have inherited a poor VDR
How to increase VDR activation
Compensate for poor VDR by increasing one or more:Increasing Increases 1) Vitamin D supplement Sun
Ultraviolet -BVitamin D in the blood
and thus in the cells2) Magnesium Vitamin D in the blood
AND in the cells3) Omega-3 Vitamin D in the cells 4) Resveratrol Vitamin D Receptor 5) Intense exercise Vitamin D Receptor 6) Get prescription for VDR activator
paricalcitol, maxacalcitol?Vitamin D Receptor 7) Quercetin (flavonoid) Vitamin D Receptor 8) Zinc is in the VDR Vitamin D Receptor 9) Boron Vitamin D Receptor ?,
etc10) Essential oils e.g. ginger, curcumin Vitamin D Receptor 11) Progesterone Vitamin D Receptor 12) Infrequent high concentration Vitamin D
Increases the concentration gradientVitamin D Receptor 13) Sulfroaphane and perhaps sulfur Vitamin D Receptor 14) Butyrate especially gut Vitamin D Receptor 15) Berberine Vitamin D Receptor Note: If you are not feeling enough benefit from Vitamin D, you might try increasing VDR activation. You might feel the benefit within days of adding one or more of the above
Far healthier and stronger at age 72 due to supplements Includes 6 supplements that help the VDR
This study was referenced 13 times by April 2021
Download the PDF from VitaminDWiki
Objective: In this study, we aimed to evaluate vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder (ADHD).
Patients and methods: In this cross-sectional study, a total of 80 children including 40 ADHD patients (aged 6-12 years; 28 males and 12 females) and 40 age-, sex-, and season of blood collection-matched controls (aged 6-12 years; 25 males and 15 females) were enrolled. Serum vitamin D and vitamin D receptor levels and calcium, phosphorus, and alkaline phosphatase were measured. The vitamin D receptor levels in the serum were measured using the quantitative sandwich enzyme immunoassay technique.
Results: Serum vitamin D and vitamin D receptor levels were found to be significantly lower in children with ADHD compared to healthy controls. No significant differences were found in serum calcium, phosphorus, and alkaline phosphatase levels. No significant differences were found among the ADHD subtypes in terms of serum vitamin D, vitamin D receptor, calcium, phosphorus and alkaline phosphatase levels.
Conclusion: This study suggests that children with ADHD have lower levels of vitamin D and vitamin D receptor. According to the authors’ knowledge, this is the first study to describe vitamin D receptor levels in ADHD.
Start of Introduction
Characterized by attention deficit and hyperactivity/impulsivity symptoms, attention- deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder with childhood onset likely to persist into the adulthood. A comprehensive meta-analysis has estimated its prevalence to be 5.29%.1 It is almost three times more common in men than in women.2 Although it is a common disease, its etiology still remains largely unknown. Family, twin, adoption, and candidate gene studies have shown that genetic factors play a major role in the disease onset.3 In addition, various trace element deficiencies, vitamin deficiencies, polyunsaturated fatty acid deficiencies, and chemical exposures are blamed in its etiology.4 Furthermore, vitamin deficiencies are among the most discussed topics lately. In particular, vitamin D abnormalities are blamed in the etiology.5
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